pentobarbital will minimize the extent or effect of pantoprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
Contraindicated (one)pentobarbital will lessen the extent or outcome of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Keep track of Carefully (1)pentobarbital will decrease the level or effect of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (1)pentobarbital will reduce the level or influence of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is responsible for the formation and elimination of cariprazine's active metabolites.
Contraindicated (one)pentobarbital will lower the extent or impact of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Steer clear of coadministration. Sturdy or moderate CYP3A inducers may perhaps lower cobimetinib systemic publicity by >eighty% and decrease its efficacy.
Medicines that have step therapy related to Each individual prescription. This restriction typically calls for that selected criteria be met ahead of acceptance for the prescription.
pentobarbital will lessen the level or result of brexpiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Double brexpiprazole dose above one-two weeks if administered with a robust CYP3A4 inducer.
pentobarbital will minimize the extent or outcome of eltrombopag by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.
pentobarbital will lessen the extent or impact of estradiol vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will reduce the level or effect of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with strong CYP3A4 inducers just isn't advised
pentobarbital will lessen the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
Keep an eye on Carefully (one)pentobarbital will minimize the level or result of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Caution when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone may perhaps increase and may result in most likely lethal respiratory depressionSerious - Use Option (one)hydrocodone, pentobarbital.
Keep track of Closely (one)pentobarbital will lower the extent or outcome of more info tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Loss of, or lowered reaction to tofacitinib may come about when coadministered with potent CYP3A4 inducers
pentobarbital will lessen the level or outcome of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers may perhaps minimize partiaprevir and ritonavir ranges, and as a consequence diminished efficacy of Viekira Pak